X-ray structure of LFA-1 I-domain in complex with LFA878 at 2.1A resolution
收藏Protein Data Bank Japan2023-10-25 更新2026-03-21 收录
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X-ray structure of LFA-1 I-domain in complex with LFA878 at 2.1A resolution Descriptor: (1S,3R,8AS)-8-(2-{(4S,6S)-3-(4-HYDROXY-3-METHOXYBENZYL)-4-[2-(METHYLAMINO)-2-OXOETHYL]-2-OXO-1,3-OXAZINAN-6-YL}ETHYL)-3 ,7-DIMETHYL-1,2,3,7,8,8A-HEXAHYDRONAPHTHALEN-1-YL (2R)-2-METHYLBUTANOATE, Integrin alpha-L, MAGNESIUM ION Authors: Weitz-Schmidt, G, Welzenbach, K, Dawson, J, Kallen, J. Deposit date: 2004-09-06 Release date: 2004-09-21 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Improved lymphocyte function-associated antigen-1 (LFA-1) inhibition by statin derivatives: molecular basis determined by x-ray analysis and monitoring of LFA-1 conformational changes in vitro and ex vivo J.Biol.Chem., 279, 2004
创建时间:
2004-09-06



