Crystal structure of estrogen receptor alpha in complex with receptor degrader 6
收藏Protein Data Bank Japan2023-11-01 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/6wok
下载链接
链接失效反馈官方服务：
资源简介：
Crystal structure of estrogen receptor alpha in complex with receptor degrader 6 Descriptor: (1R,3R)-1-(2,6-difluoro-4-{2-[3-(fluoromethyl)azetidin-1-yl]ethoxy}phenyl)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1H-beta-carboline, (2S)-3-(3-hydroxyphenyl)-2-(4-iodophenyl)-4-methyl-2H-1-benzopyran-6-ol, Estrogen receptor Authors: Kiefer, J.R, Vinogradova, M, Liang, J, Zhang, B, Wang, X, Labadie, S. Deposit date: 2020-04-24 Release date: 2020-07-01 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.309 Å) Cite: Discovery of GNE-149 as a Full Antagonist and Efficient Degrader of Estrogen Receptor alpha for ER+ Breast Cancer. Acs Med.Chem.Lett., 11, 2020
创建时间：
2020-04-24
