Real-Time Closed-Loop Feedback System For Mouse Mesoscale Cortical Signal And Movement Control: CLoPy

This dataset includes raw wide-field GCaMP6s image stacks of dorsal cortical activity in mice while they are being trained in 1) A closed-loop neurofeedback task (CLNF) and 2) A closed-loop movement feedback task (CLMF). Data for CLMF experiments are accompanied by synchronized behavior recordings of the whole body of the mouse. Most experiments were performed toward the end of the mouse light cycle(5 PM - 8 PM). CLNF cortical image stacks were collected using Raspberry Pi camera v1 while CLMF cortical image stacks were recorded using a pair of front-to-front video lenses coupled to a CCD camera (Pantera Dalsa). Calcium indicators were excited with blue-light-emitting diodes (470 nm) with bandpass filters (467–499 nm). Emission fluorescence was filtered using a 510–550 nm bandpass filter. The recorded behavior scene was illuminated with infrared light. This is the data repository for titled publication "Real-Time Closed-Loop Feedback System For Mouse Mesoscale Cortical Signal And Movement Control: CLoPy".