Crystal structure of the human nucleoside diphosphate kinase B domain in complex with the product AT-8500 formed by catalysis of compound AT-9010

Crystal structure of the human nucleoside diphosphate kinase B domain in complex with the product AT-8500 formed by catalysis of compound AT-9010 Descriptor: GLYCEROL, Nucleoside diphosphate kinase B, [(2~{R},3~{R},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-4-fluoranyl-4-methyl-3-oxidanyl-oxolan-2-yl]methyl phosphono hydrogen phosphate Authors: Feracci, M, Chazot, A, Ferron, F, Alvarez, K, Canard, B. Deposit date: 2023-06-21 Release date: 2024-07-31 Last modified: 2024-09-04 Method: X-RAY DIFFRACTION (1.9 Å) Cite: The activation cascade of the broad-spectrum antiviral bemnifosbuvir characterized at atomic resolution. Plos Biol., 22, 2024