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Modeling and drug targeting of a myeloid neoplasm with atypical 3q26/MECOM rearrangement using patient-specific iPSCs

NIAID Data Ecosystem2026-05-02 收录

iPSC疾病模型

MECOM基因重排

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE248240 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2025-01-23

ALS疾病分子机制

iPSC疾病模型

We established iPSCs from healthy donors, FUS-ALS and SOD1-ALS patients. Using our differentiation protocol originally developed by Reinhardt et al.,2013, we diferentiated these iPSCs toward spinal mo

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HiSeq_LDLR_iCG038A

家族性高胆固醇血症基因测序

iPSC疾病模型

HiSeq_LDLR_ICGi038-A IPSC FH 5.1.2Sh and MNC FH 5.1.2Sh

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Gene expression analysis of human iPSC generated from pathogenic LRRK2 (G2019S) mutation bearing patients

帕金森病基因表达

iPSC疾病模型

Genetic mutations on leucine-rich repeat kinase 2 (LRRK2) have been associated with an increased risk of Parkinson's disease. The Gly2019Ser (G2019S) mutation on LRRK2 gene is a relatively common caus

NIAID Data Ecosystem50

Gene expression data from human fibroblasts and induced Pluripotent Stem cells from amyotrophic lateral sclerosis patients. Homo sapiens

ALS分子机制

iPSC疾病模型

We have generated human induced Pluripotent Stem cells (hiPSc) from amyotrophic lateral sclerosis (ALS, motor neuron disease) patients, using Sendai virus-mediated delivery of reprogramming factors. h

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Personalized genome sequencing coupled with iPSC technology identifies GTDC1 as a gene involved in Neurodevelopmental Disorders. Homo sapiens

神经发育障碍分子机制

iPSC疾病模型

The cellular and molecular mechanisms underlying neurodevelopmental conditions such as autism spectrum disorders have been studied intensively for decades. The ability to generate patient-specific ind

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Modeling and drug targeting of a myeloid neoplasm with atypical 3q26/MECOM rearrangement using patient-specific iPSCs

资源简介：

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