Representation of sequences in naïve pools.^a

a. See Table S1 for a more extensive list and details o calculations. b. m = length of randomized sequence. c. U = 4m, the number of possible unique sequences. d. R = the average representation of each unique molecule in a pool, for the indicated (0.1 or 25) nmol of total strands. e. Beyond diversity limit; some possible sequences are absent. f. Beyond synthesizer limit for 1 µmol scale synthesis; some sequences are not produced.