Genome-wide analysis of Bcl11a regulation genes in bone marrow derived pro-B cells
收藏官方服务：
资源简介：
Genome-wide analysis of Bcl11a regulation genes in bone marrow derived pro-B cells
应用场景：
创建时间：
2012-09-11
相关数据集
Phospholipase Cγ pathway-dependent mTOR signaling controls IL-7-mediated early B cell development. Mus musculus
We examined the global gene expression profile of PLCγ1/PLCγ2 double-deficient CLPsand B cell progenitors by RNA-seq analysis. Overall design: CLPs (Lin-IL-7R+) and B cell progenitors (B220+IgM-IL-7R+
NIAID Data Ecosystem100
Polypyrimidine tract binding proteins are essential for B cell development. Polypyrimidine tract binding proteins are essential for B cell development
During B cell development, recombination of immunoglobulin loci is tightly coordinated with the cell cycle to avoid unwanted rearrangements of other genomic locations. Several factors have been identi
NIAID Data Ecosystem50
Induction of extracellular adenosine salvage and metabolic quiescence regulate the transitional to follicular B cell checkpoint in humans.
Transcriptional profiling of transitional and follicular B cells showed that metabolic quiescence was acquired at the follicular B cell stage in both humans and mice, characterized by an orchestrated
NIAID Data Ecosystem10
The spliceosome component Usp39 controls B cell development by regulating immunoglobulin gene rearrangement. The spliceosome component Usp39 controls B cell development by regulating immunoglobulin gene rearrangement
The spliceosome is a large ribonucleoprotein complex responsible for pre-mRNA splicing and genome stability maintenance. Disruption of the spliceosome activity may lead to developmental disorders and
NIAID Data Ecosystem60
BCR and TLR-induced IRF1 promotes T cell independent B cell responses by supporting Notch2 dependent Marginal Zone B cell development
The prototypic interferon (IFN)-inducible transcription factor, IRF1, not only controls expression of IFN genes but also regulates T cell and macrophage fate specification and function. We show that I
NIAID Data Ecosystem40
