Rat chondrocytes were divided into control group (RP), thrombin group (RPT), and thrombin plus inhibitor group (RPTi). The differential genes were identified by RNA-sequencing, and verified by western

NIAID Data Ecosystem40

Asialoglycoprotein receptor 1 functions as a tumor suppressor in liver cancer via inhibition of STAT3

肝癌抑癌机制

STAT3信号通路

Liver cancer is characterized by aggressive growth and high mortality. Asialoglycoprotein receptor 1 (ASGR1), which is expressed almost exclusively in liver cells, is reduced in liver cancer. However,

NIAID Data Ecosystem40

A new mixed-ligand Co(II) coordination polymer: treatment activity on ulcerative colitis by inhibiting the JAK2/STAT3 signaling pathway in the colonic epithelial cells

STAT3信号通路

结肠炎治疗

In the current study, a novel mixed-ligand coordination polymer, {[Co(L)(dpe)]·(ClO 4 )} ( 1 ) (H 2 LCl = 3-carboxy-1-(3-carboxybenzyl)pyridin-1-ium, dpe = (E)-1,2-di(pyridin-4-

DataCite Commons2024-02-15 更新60

miR181a is a novel key player in the STAT3 mediated survival network of TCRab CD8+ T-LGL leukemia [sRNA-Seq]. miR181a is a novel key player in the STAT3 mediated survival network of TCRab CD8+ T-LGL leukemia [sRNA-Seq]

白血病分子机制

STAT3信号通路

TCRαβ CD8 large granular lymphocyte (LGL) leukemia is a rare heterogeneous hematological disorder with a chronic disease course that mostly affects elderly. It is generally accepted that LGL cells ari

NIAID Data Ecosystem40

Additional file 8 of MAFF alleviates hepatic ischemia–reperfusion injury by regulating the CLCF1/STAT3 signaling pathway

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