Single-Cell Analyses Elucidate the Cellular and Molecular Landscape of Ulcerative Colitis
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE125527
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Inflammatory bowel disease (IBD) encompasses a spectrum of complex intestinal disorders characterized by dysregulated host innate and adaptive immune responses to gut microbiota in genetically susceptible hosts. We generated an integrated single-cell (scRNA-seq, scTCR-seq, and scBCR-seq) resource dataset that revealed key cellular components and cell states of the gastrointestinal mucosal and peripheral immune systems in health and ulcerative colitis (UC). Single-cell RNA-seq and BCR/TCR repertoire analyses of immune cell from 15 patients
创建时间:
2020-09-14



