Crystal structure KPC-2 beta-lactamase complexed with WCK 5107 by soaking
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Crystal structure KPC-2 beta-lactamase complexed with WCK 5107 by soaking Descriptor: (2S,5R)-1-formyl-N'-[(3R)-piperidine-3-carbonyl]-5-[(sulfooxy)amino]piperidine-2-carbohydrazide, 1,2-ETHANEDIOL, CITRIC ACID, ... Authors: van den Akker, F, Nguyen, N.Q. Deposit date: 2017-09-18 Release date: 2018-08-01 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Strategic Approaches to Overcome Resistance against Gram-Negative Pathogens Using beta-Lactamase Inhibitors and beta-Lactam Enhancers: Activity of Three Novel Diazabicyclooctanes WCK 5153, Zidebactam (WCK 5107), and WCK 4234. J. Med. Chem., 61, 2018
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2017-09-18
