Codon Usage Bias in SARS-CoV-2 Spike Gene: A 9-Million-Genome Analysis

This dataset contains codon usage bias (CUB) analysis from ~9 million SARS-CoV-2 genomes, focusing on the Spike protein. The data is split into 188 chunks (cub_spike_chunk_*.tsv) and includes: Codon frequency per amino acidRelative synonymous codon usage (RSCU)Top accessions associated with each codon etc. For the study of viral evolution, translational regulation, and host adaptation. Data format: TSV files 188 x 50,000 chunks | Derived from GISAID/NCBI sequences | Data Normalized via GVAtlas | Collected 2020–2024