Notes: 1) Knockdown phenotypes in 3T3 fibroblasts, 3T3-L1 adipocytes, and MMH-D3 hepatocytes are from this study, and those in U2OS osteosarcoma cells are from [27], [31]. 2) Detailed circadian parame
Summary of silencing phenotypes of Sir4 C-terminal constructs on different reporters and backgrounds. Qualitative silencing strength is given (+++: same level as full length SIR4, ++intermediate silen
− not significant in comparison with three controls (UAS, GAL4 and short Q). ± significant but slight (<20%) difference. + less than 2 fold difference. ++ more than 2 fold difference. +++ more than 3
