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HCV NS3-4A protease domain complexed with a macrocyclic ketoamide inhibitor, SCH419021

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Protein Data Bank Japan2024-11-20 更新2026-03-21 收录
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https://pdbj.org/mine/summary/2gvf
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HCV NS3-4A protease domain complexed with a macrocyclic ketoamide inhibitor, SCH419021 Descriptor: (6R,8S,11S)-11-CYCLOHEXYL-N-(1-{[(2-{[(1S)-2-(DIMETHYLAMINO)-2-OXO-1-PHENYLETHYL]AMINO}-2-OXOETHYL)AMINO](OXO)ACETYL}BUTYL)-10,13-DIOXO-2,5-DIOXA-9,12-DIAZATRICYCLO[14.3.1.1~6,9~]HENICOSA-1(20),16,18-TRIENE-8-CARBOXAMIDE, Polyprotein, ZINC ION, ... Authors: Arasappan, A, Njoroge, F.G, Chen, K.X, Venkatraman, S, Parekh, T.N, Gu, H, Pichardo, J, Butkiewicz, N, Prongay, A, Madison, V, Girijavallabhan, V. Deposit date: 2006-05-02 Release date: 2007-01-23 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.5 Å) Cite: P2-P4 macrocyclic inhibitors of hepatitis C virus NS3-4A serine protease. Bioorg.Med.Chem.Lett., 16, 2006
创建时间:
2006-05-02
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