Treg-cell percentages and IL-10 production for Pp3, TLRnlig, TLRnlig-Pp3 and TLRnlig plus Pp3 for allergic patients

Data indicated significantly higher percentages of Treg cells and IL-10 production in allergic patient compared to tolerant controls when stimulated with both TLRnlig-Pp3. Moreover, these effects were higher compared to Pp3 peptide alone, TLRnlig as well as TLRnlig plus Pp3 only in allergic patients except with TLR4lig-Pp3 for the IL-10 production. Regarding the TLR4 activation, they can induce a low production of IL-10.