Protection of mice from death, clinical score and serology results after single dose vaccination with MVA H5 recombinants.

(1)Mice were vaccinated once with 106 pfu of recombinant MVA or wt MVA; for abbreviations see Tables 2 and 3;(2)challenge dose, 1×105 TCID50; for abbreviations see Table 1;(3)n/nt, number of survivors/total animals of two separate experiments with 6 animals per group;(4)clinical score at day 8 (peak)/day 14 (the end of experiment) after challenge. Each number represents the arithmetic mean from 12 animals;(5)final serum dilutions in µNT assay were 1∶20 (dl 14), in all other sera 1∶10 (detection limit