The formulas used to calculate the concentration vs. time curves and the kinetic parameters in a first order absorption process in an one-compartment model.

Ct, D-[6,6-2H]-glucose concentration at time point t; Mt, fractional contribution of D-[6,6-2H]-glucose at time point t; [glc]t, blood glucose concentration at time point t. C(0)ab, initial concentration of D-[6,6-2H]-glucose determined by extrapolation of the absorption period; C(0)el, initial concentration of D-[6,6-2H]-glucose determined by extrapolation of the elimination period; kab, absorption rate constant; kel, absorption rate constant. D, dose D-[6,6-2H]-glucose administrated; BG, average blood glucose concentration during the test; Ra = EGP.The formulas used to calculate the concentration vs. time curves and the kinetic parameters in a first order absorption process in an one-compartment model.