Determining the nanoBRET AL2K IC50 values of 24 new ACVR1/ALK2 inhibitors
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In an effort to develop clinical compounds for Diffused Intrinsic Pontine Glioma (DIPG) treatment, new analogues of ACVR1/ALK2 inhibitors are continuously synthesised by Ontario Institute for Cancer Research (OICR) and Charles River Laboratories (CRL). I will provide prompt feedback of the cellular assay results to guide their design of new compounds. The blog post for this page can be found on the SGC opennotebook site: https://openlabnotebooks.org/determining-the-nanobret-al2k-ic50-values-of-24-new-acvr1-alk2-inhibitors/
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Zenodo创建时间：
2018-12-19
