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Junction site NGS of site-directed knock-in of DNA cargo using HMEJ

NIAID Data Ecosystem2026-05-01 收录

定点基因敲入

细胞基因组编辑

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP465959 数据链接链接失效反馈

官方服务：

资源简介：

Sequencing reads of the 5 and 3-prime ends of site-directed cargo insertion in engineered human T cells.

应用场景：

创建时间：

2023-10-14

细胞基因组编辑

免疫反应

Dendritic cells (DCs) are central regulators of both innate and adaptive immunity and as such play roles in processes ranging from antitumor immunity to regulation of host-microbiome communication at

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Homo sapiens Raw sequence reads. Homo sapiens

HIV整合位点

细胞基因组编辑

Raw sequence read of HIV insertion sites into the genome of HEK293T and HOS cells

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Efficient and multiplexed somatic genome editing with Cas12a mice

细胞基因组编辑

癌症模型构建

Somatic genome editing in mouse models has increased our understanding of the in vivo effects of genetic alterations in areas ranging from neuroscience to cancer biology and beyond. However, existing

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Efficient genome editing in erythroid cells unveils novel MYB target genes and regulatory functions. Efficient genome editing in erythroid cells unveils novel MYB target genes and regulatory functions

细胞基因组编辑

转录因子调控网络

Targeted genome editing holds great promise in biology. However, efficient genome modification, including gene knock-in, remains an unattained goal in multiple cell types and loci due to poor transfec

NIAID Data Ecosystem50

Effects of anionic polymer-stabilized Cas9 RNPs on off-target genome modifications at EMX1

CRISPR-Cas9脱靶

细胞基因组编辑

The anionic polymers PGA or ssODNenh can increase NHEJ editing efficiency, including at off-target sites. CD3+ T cells isolated from two healthy donors were treated with regular, PGA-stabilized, or ss

NIAID Data Ecosystem40

Junction site NGS of site-directed knock-in of DNA cargo using HMEJ

资源简介：

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