A genome-scale single cell CRISPRi map of trans gene regulation across many human pluripotent stem cell lines (Transcriptional Changes)

This data-set is post-processed from two Perturb-seq experiments - one genome-wide screen and another targeted screen - conducted in multiple iPSC lines, described in (https://www.biorxiv.org/content/10.1101/2024.11.28.625833v1). The following data summaries are available:<b>[Genome-wide screen]</b> Mean transcriptional fold-change per targets and expressed gene.<b>[Genome-wide screen]</b> Mean transcriptional fold-change per guide and expressed gene.<b>[Genome-wide screen]</b> Co-regulation (R2) of targets.<b>[Genome-wide screen]</b> Co-perturbation (R2) of expressed genes.<b>[Targeted screen]</b> Mean transcriptional fold-change per target across cell lines, per expressed gene.<b>[Targeted screen]</b> Mean transcriptional fold-change per guide across cell lines, per expressed gene.<b>[Targeted screen]</b> Mean transcriptional fold-change per target, per cell line, per expressed gene.