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Fab/epitope complex structure of rabbit monoclonal antibody R53 targeting an epitope in HIV-1 gp120 C4 region

NIAID Data Ecosystem2026-05-02 收录

HIV-1抗体

抗体-表位复合物

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Fab/epitope complex structure of rabbit monoclonal antibody R53 targeting an epitope in HIV-1 gp120 C4 region

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创建时间：

2024-10-30

结构生物学

HIV-1抗体

Crystal structure of strain-specific glycan-dependent CD4 binding site-directed neutralizing antibody CAP257-RH1, in complex with HIV-1 strain RHPA gp120 core with an oligomannose N276 glycan. Descrip

Protein Data Bank Japan2024-10-30 更新40

Summary of VHH binding to HIV-1 envelope proteins.

HIV-1抗体

抗体亲和力检测

The amount of VHH required to give half-maximal A490 was estimated from the respective binding curves. +++ half-maximal binding at 10 µg/mL; -, no binding was obser

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Gp120/CD4 Blocking Antibodies Are Frequently Elicited in ART-Naïve Chronically HIV-1 Infected Individuals

HIV-1抗体

疫苗抗原设计

Antibodies with the ability to block the interaction of HIV-1 envelope glycoprotein (Env) gp120 with CD4, including those overlapping the CD4 binding site (CD4bs antibodies), can protect from infectio

Figshare2016-01-15 更新20

Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape

HIV-1抗体

病毒逃逸机制

A comprehensive understanding of the regions on HIV-1 envelope trimers targeted by broadly neutralizing antibodies may contribute to rational design of an HIV-1 vaccine. We previously identified a par

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Crystal structure of chimeric germ-line precursor of NIH45-46 Fab in complex with gp120 of 93TH057 HIV-1

HIV-1抗体

病毒蛋白

Crystal structure of chimeric germ-line precursor of NIH45-46 Fab in complex with gp120 of 93TH057 HIV-1 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain, ... Aut

Protein Data Bank Japan2024-11-20 更新30

Fab/epitope complex structure of rabbit monoclonal antibody R53 targeting an epitope in HIV-1 gp120 C4 region

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