Crystal structure of the VEGFR2 kinase domain in complex with a benzimidazole inhibitor
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Crystal structure of the VEGFR2 kinase domain in complex with a benzimidazole inhibitor Descriptor: 4-[[2-[[4-chloro-3-(trifluoromethyl)phenyl]amino]-3H-benzimidazol-5-yl]oxy]-N-methyl-pyridine-2-carboxamide, Vascular endothelial growth factor receptor 2 Authors: Whittington, D.A, Kim, J.L, Long, A.M, Rose, P, Gu, Y, Zhao, H. Deposit date: 2007-08-03 Release date: 2007-09-25 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Design, Synthesis, and Evaluation of Orally Active Benzimidazoles and Benzoxazoles as Vascular Endothelial Growth Factor-2 Receptor Tyrosine Kinase Inhibitors. J.Med.Chem., 50, 2007
创建时间:
2007-08-03



