CARMA1 recruits MALT1 and BCL10 forming CBM Complex
收藏reactome.org2025-03-23 收录
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CARMA1 is phosphorylated and recruits BCL10 and MALT1 to the plasma membrane to form the CBM complex (Sommer et al. 2005, Tanner et al. 2007). Evidence from T cells (Jurkat cells) indicates that MALT1 and BCL10 oligomerize to activate the IKK complex (Zhou 2004).
CARMA1被磷酸化,并招募BCL10和MALT1至质膜上,以形成CBM复合物(Sommer等,2005年,Tanner等,2007年)。来自T细胞(Jurkat细胞)的证据表明,MALT1和BCL10会形成寡聚体以激活IKK复合物(Zhou,2004年)。
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