Summary MaxQ* statistics in genomes having and lacking specific NAPs in all analyzed genomes.

Mean MaxQ* values assessed by the “A2T2” method and standard deviations are shown for groups of genomes possessing and lacking a homolog of each NAP. N signifies the number of genomes in each group. Presence of absence of each NAP in a genome is based on data from the KEGG database ([17], http://www.genome.jp/linkdb/). ‘Interaction mode’ specifies whether the NAP forms bridges or bends upon interaction with DNA (adapted from [1]). Statistical significance of the differences was assessed by Man-Whitney U-test. Data corresponding to p-values ≥0.05 are in parentheses. DNA-bridging NAPs are in the top part of the table.aThe ratio of genomes with and without the NAP is unbalanced (>10 or bFis can form both bridges and bends.cDps and CbpA have not been confirmed to form bridges or bends.