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Crystal structure of MCL-1 in complex with a BIM competitive inhibitor

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Protein Data Bank Japan2024-03-13 更新2026-03-21 收录
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Crystal structure of MCL-1 in complex with a BIM competitive inhibitor Descriptor: 7-(2-methylphenyl)-1-[2-(morpholin-4-yl)ethyl]-3-{3-[(naphthalen-1-yl)oxy]propyl}-1H-indole-2-carboxylic acid, Induced myeloid leukemia cell differentiation protein Mcl-1 Authors: Judge, R.A, Souers, A.J. Deposit date: 2017-09-27 Release date: 2017-10-04 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structure-guided design of a series of MCL-1 inhibitors with high affinity and selectivity. J. Med. Chem., 58, 2015

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2017-09-27
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