Transcriptomic effects of the cell cycle regulator LGO in Arabidopsis sepals. Arabidopsis thaliana strain:Columbia-0 (Col-0)

This study analyses the effects of gene activity in Arabidopsis thaliana sepals of overexpressing a cell cycle regulator, LGO/SMR1. Sepals are the protective organs of flowers in the thale cress A. thaliana; LGO/SMR1 is an inhibitor of cyclin-dependent kinases (CDKs) from the SIAMESE-related (SMR) family. The effects of LGO overexpression were observed both in a wild-type genetic background, and in a background mutant for the transcriptional regulator ATML1 (which itself, in normal sepals, acts in concert with LGO to promote endoreduplicated giant cell fates). Previous genetic work has shown that overexpression of LGO in sepals can drive endoreduplicated giant cell fate directly; this study analyzes the possible transcriptomic underpinnings of this developmental phenomenon.