Sequential ligand-dependent Notch signaling activation regulates valve primordium formation and morphogenesis
收藏NIAID Data Ecosystem2026-03-13 收录
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资源简介：
Our studies identify a mechanism of signaling crosstalk during valve morphogenesis that sheds light on the origin of congenital heart defects associated with reduced Notch function. Overall design: Aortic and pulmonary cardiac valves were isolated by laser microdissection from WT and Jag1flox;Nkx2.5-Cre mouse embryos at stage E14.5, and their expression profile characterized by RNA-Seq.
创建时间：
2022-09-09
