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Methylome study in Nasopharyngeal Carcinoma (NPC). Homo sapiens

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NIAID Data Ecosystem2026-03-09 收录
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Aberrant methylation at the promoter region of tumor suppressors is frequently reported in NPC; however, genome-wide methylation changes have not been comprehensively investigated. Therefore, we systematically analyzed methylome data in 25 primary NPC tumors and non-tumor counterparts using Illumina HumanMethylation450 BeadChip. Overall design: Bisulphite converted DNA from 50 samples were hybridized to the Illumina HumanMethylation450 BeadChip. Bisulphite pyrosequencing was used as an independent method to validate the BeadChip results.

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2014-10-15
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