Crystal structure of human ROR gamma LBD in complex with a quinoline sulfonamide inverse agonist
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Crystal structure of human ROR gamma LBD in complex with a quinoline sulfonamide inverse agonist Descriptor: (2~{S})-1-[2,4-bis(chloranyl)-3-[[4-imidazol-1-yl-2-(trifluoromethyl)quinolin-8-yl]oxymethyl]phenyl]sulfonyl-~{N}-methyl-pyrrolidine-2-carboxamide, Nuclear receptor ROR-gamma Authors: Ciesielski, F, Amaudrut, J, Argiriadi, M.A, Barth, M, Breinlinger, E.C, Calderwood, D.J, Cusack, K.P, Kort, M.E, Montalbetti, C, Potin, D, Poupardin, O, Spitzer, L. Deposit date: 2018-12-03 Release date: 2019-05-29 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.99 Å) Cite: Discovery of novel quinoline sulphonamide derivatives as potent, selective and orally active ROR gamma inverse agonists. Bioorg.Med.Chem.Lett., 29, 2019
创建时间：
2018-12-03
