Histological measurements: Mean ± SD.

N = number of rats/group is indicated in the brackets.(a) Lesion volume is expressed in percent compared to the contralateral intact section of the brain.(b) von Willebrand factor (vWF) is a marker for blood vessels. Density of vWF vessels in IBZ (vessels/mm2).(c) Synaptophysin, a marker of synapses, is expressed in % of cells in the IBZ.(d) Apoptosis is expressed as the number of apoptotic cells per mm2.(e) Bielschowski and luxol Fast Blue are markers of axon and myelin, respectively, and indicate changes in axonal myelination. Data is represented as % of contralateral intact IBZ.* = significant differences, p** = significant differences, p