Crystal structure of the multidrug binding protein QacR bound to dequalinium

NIAID Data Ecosystem2026-05-01 收录

药物-蛋白复合物结构解析

多药耐药机制

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Crystal structure of the multidrug binding protein QacR bound to dequalinium

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2024-04-03

Structure of HIV-1 RT Q151M mutant

HIV逆转录酶结构解析

多药耐药机制

Structure of HIV-1 RT Q151M mutant Descriptor: RT p51 subunit, RT p66 subunit Authors: Nakamura, A, Tamura, N, Yasutake, Y. Deposit date: 2015-04-27 Release date: 2015-11-11 Last modified: 2023-11-08

Protein Data Bank Japan2023-11-08 更新60

Changes in the expression of miR-381 and miR-495 are inversely associated with the expression of the MDR1 gene and development of multi-drug resistance. Homo sapiens

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Multidrug resistance (MDR) frequently develops in cancer patients exposed to chemotherapeutic agents and is usually brought about by over-expression of P-glycoprotein (P-gp) which acts as a drug efflu

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Drug Export Pathway of Multidrug Exporter AcrB Revealed by DARPin Inhibitors - Table 1

多药耐药机制

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Data Collection and Refinement Statistics

Figshare2016-10-28 更新30

Crystal Structure of BmrR bound to ethidium

蛋白质晶体

多药耐药机制

Crystal Structure of BmrR bound to ethidium Descriptor: 23 bp promoter, ETHIDIUM, GLYCEROL, ... Authors: Bachas, S, Eginton, C, Gunio, G, Wade, H. Deposit date: 2010-12-20 Release date: 2011-06-15 Las

Protein Data Bank Japan2024-02-21 更新60

Kinetic Validation of the Models for P-Glycoprotein ATP Hydrolysis and Vanadate-Induced Trapping. Proposal for Additional Steps

P-糖蛋白动力学建模

多药耐药机制

P-Glycoprotein, a member of the ATP-binding cassette (ABC) superfamily, is a multidrug transporter responsible for cellular efflux of hundreds of structurally unrelated compounds, including natural pr

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Crystal structure of the multidrug binding protein QacR bound to dequalinium

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