Comparison of the percent homologies (%) of the complete HSFY protein (A) and HSF-type DNA-binding domain (B), for all species analyzed.

In all cases, the percent homology was highest at the conserved HSF-type DNA-binding domain with the exception of an analysis of the two human HSFY copies which showed that both the complete protein sequence and conserved region were identical (100% homology). Bovine showed 51% and 72% homology with human HSFY for the complete protein and conserved domain, respectively. Bovine HSFY was most closely related to cat HSFY with a complete protein homology and conserved domain homology of 58% and 81%, respectively. The accession numbers for the proteins found in the NCBI database are as follows: human hHSFY1: NP_149099.2; hHSFY2: NP_714927.1, mouse NP_081937.1, rat NP_001012132.1, rhesus macaque ACL51668.1, cat NP_001035212.1, bovine NP_001070474.1.