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Paternal overdiet drives intergenerational transmission of metabolic disorders through sperm epigenetic alteration [MeDIP-Seq]

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NIAID Data Ecosystem2026-04-25 收录
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We using a mouse model of paternal famine to simulate famine, our data show that paternal famine increases the susceptibility to metabolic disease in offspring through gametic epigenetic alterations. Overall design: Sperm DNA profiles of 12 week old control male F0 and Famine male F0 mice were generated by deep sequencing

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2019-06-14
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