Tet2 negatively regulates memory fidelity
收藏NIAID Data Ecosystem2026-04-30 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP230428
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资源简介:
Tet2 functions in the CA1 as a negative regulator of long-term memory, and its haploinsufficiency in glutamatergic neurons or knockdown across the CA1 in mice is sufficient to enhance the fidelity of hippocampal-dependent spatial and associative memory. Overall design: Changes in DNA methylation was determined using whole genome bisulfite sequencing from glutamatergic Tet2 haploinsufficient CA1 tissue from mice.
创建时间:
2022-11-16



