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Thermal 1,3-Trityl Migrations in Diels−Alder Domino Reactions of 1-Trityl-4-vinyl-1<i>H</i>-imidazoles

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NIAID Data Ecosystem2026-03-06 收录
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Under thermal conditions, tritylimidazoles have been shown to undergo sterically driven N→N trityl migrations, in disagreement with previously published reports. These migrations are a key step in several highly diastereoselective domino reaction sequences (Diels−Alder, [1,3]-H shift, [1,3]-trityl migration and Diels−Alder, [1,3]-H shift, [1,3]-trityl migration, Michael reaction) leading to architecturally complex molecules.

创建时间:
2016-02-24
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