the whole transcriptome of HL-60 cell host invaded by Anplasma phagocytophilum metagenome

The whole transcriptome profiles of HL-60 cells infected with A. phagocytophilum were obtained in this study. The results of the GO and KEGG pathway analyses suggest significant roles for these dif-RNAs during the course of A. phagocytophilum infection. A ceRNA regulation network containing miRNA at its center was constructed for the first time, with hsa-miR-4518 and hsa-miR-3609 being the crucial miRNAs. These findings provide novel insights into the responses of human intestinal epithelial cells to A. phagocytophilum infection.