Fecal microbiota transplantation protects renal ischemia reperfusion injury

NIAID Data Ecosystem2026-05-02 收录

缺血再灌注损伤

粪菌移植治疗

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA1215045 数据链接链接失效反馈

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Renal ischemia reperfusion injury (IRI) is a pathophysiological phenomenon in which renal ischemic tissues regain their blood supply and tissue damage is aggravated.

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2025-01-24

Protective role of silent information regulator 1 against hepatic ischemia: effects on oxidative stress injury, inflammatory response, and MAPKs

缺血再灌注损伤

氧化应激与炎症

Objective : Previous studies have verified that silent information regulator 1 (SIRT1), a class III histone deacetylase, protects against ischemia reperfusion (IR) injury (IRI) in some organs. I

DataCite Commons2024-03-24 更新120

Data_Sheet_1_Human Recombinant Alkaline Phosphatase (Ilofotase Alfa) Protects Against Kidney Ischemia-Reperfusion Injury in Mice and Rats Through Adenosine Receptors.PDF

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药物干预机制

Adenosine triphosphate (ATP) released from injured or dying cells is a potent pro-inflammatory “danger” signal. Alkaline phosphatase (AP), an endogenous enzyme that de-phosphorylates extracellular ATP

NIAID Data Ecosystem40

Mus musculus Raw sequence reads. Mus musculus

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巨噬细胞极化

we performed RNA-Seq using separated macrophages from kidneys of WT and Lyz-TSC1cKO groups at 24h and 2 weeks after IRI to explore the mechanisms involved in macrophage polarization.

NIAID Data Ecosystem30

Transcriptome Analysis of Renal Ischemia/Reperfusion Injury and its Modulation by Ischemic Pre-Conditioning or Hemin treatment

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缺血预处理与血红素治疗

We examined, through an oligonucleotide microarray protocol, the renal differential transcriptome profiles of mices submitted to IRI, IPC and Hemin treatment. After identifying the profiles of differe

NIAID Data Ecosystem50

Downregulation of autophagy is associated with severe ischemia-reperfusion-induced acute kidney injury in overexpressing C-reactive protein mice

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自噬调节机制

C-reactive protein (CRP), was recently reported to be closely associated with poor renal function in patients with acute kidney injury (AKI), but whether CRP is pathogenic or a mere biomarker in AKI r

NIAID Data Ecosystem40

Fecal microbiota transplantation protects renal ischemia reperfusion injury

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