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Integrated Ugi-Based Assembly of Functionally, Skeletally, and Stereochemically Diverse 1,4-Benzodiazepin-2-ones

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https://figshare.com/articles/dataset/Integrated_Ugi_Based_Assembly_of_Functionally_Skeletally_and_Stereochemically_Diverse_1_4_Benzodiazepin_2_ones/2208325
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资源简介:
A practical, integrated and versatile U-4CR-based assembly of 1,4-benzodiazepin-2-ones exhibiting functionally, skeletally, and stereochemically diverse substitution patterns is described. By virtue of its convergence, atom economy, and bond-forming efficiency, the methodology documented herein exemplifies the reconciliation of structural complexity and experimental simplicity in the context of medicinal chemistry projects.
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2015-02-06
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