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A biogenesis step upstream of Microprocessor controls miR-17~92 expression

ChEBI2015-05-11 更新2026-07-21 收录

microRNA生物发生

致癌miRNA调控

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-68699 数据链接链接失效反馈

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A biogenesis step upstream of Microprocessor controls miR-17~92 expression

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创建时间：

2015-05-11

microRNA生物发生

RNA代谢调控

Protein phosphatase 4 (PP4) is a highly conserved serine/threonine protein phosphatase in yeast, plants, and animals. The composition and functions of the plant PP4 are poorly understood. Here, we unc

NIAID Data Ecosystem80

Cell-Independent MicroRNA Biogenesis

microRNA生物发生

RNA调控机制

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

NIAID Data Ecosystem50

The DGCR8-UGU interaction in microRNA biogenesis

microRNA生物发生

DGCR8

Human Microprocessor is a trimeric complex composed of the RNase III enzyme, DROSHA, and a dimer of DGCR8 (its cofactor). Microprocessor initiates the biogenesis of microRNA by processing primary micr

NIAID Data Ecosystem40

A sliding-bulge structure at the Dicer processing site of pre-miRNA regulates alternative Dicer processing to generate 5'-isomiRs (pre-miR-203)

microRNA生物发生

Dicer蛋白

5'-isomiRs expand the repertoire of miRNA targets. However, how they are generated is not well understood. Here, we showed that, for some miRNAs in mammalian cells, 5'-isomiRs are generated by alterna

NIAID Data Ecosystem80

A study of MapToCleave: high-throughput profiling of microRNA biogenesis in living cells. Kang et al. : Count table for experimental validation

microRNA生物发生

miRNA前体加工验证

count_table_for_experimental_validation.txt, Related to Figure 5. The count table of human miRNA precursors (miRBase v21) and modified miRNA precursors (Data S10) was generated as described in the me

NIAID Data Ecosystem50

A biogenesis step upstream of Microprocessor controls miR-17~92 expression

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