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Histone Demethylase-Assisted Somatic Cell Nuclear Transfer Facilitates Derivation of Human Pluripotent Stem Cells

ChEBI2016-03-01 更新2026-07-12 收录

体细胞核移植

人类多能干细胞衍生

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-73362 数据链接链接失效反馈

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资源简介：

Histone Demethylase-Assisted Somatic Cell Nuclear Transfer Facilitates Derivation of Human Pluripotent Stem Cells

应用场景：

创建时间：

2016-03-01

胚胎发育转录组学

体细胞核移植

Production of embryos with high developmental competence by somatic cell nuclear transfer (scNT) is far less efficient than for in vitro fertilized (IVF) embryos, likely due to an accumulation of erro

NIAID Data Ecosystem60

Summary of in vitro and in vivo development following SCNT with antibiotic selectable marker-free cells.

体细胞核移植

转基因动物生产

*Donor nuclei from antibiotic selectable marker-excised cells with single-copy integration of transgene into different locus, or from untransfected cells (control), were used for nuclear transfer expe

NIAID Data Ecosystem30

Data_Sheet_1_Combined Chaetocin/Trichostatin A Treatment Improves the Epigenetic Modification and Developmental Competence of Porcine Somatic Cell Nuclear Transfer Embryos.PDF

体细胞核移植

表观遗传重编程

Developmental defects in somatic cell nuclear transfer (SCNT) embryos are principally attributable to incomplete epigenetic reprogramming. Small-molecule inhibitors such as histone methyltransferase i

NIAID Data Ecosystem20

In vitro development of re-cloned SCNT embryos generated using fibroblasts derived from a transgenic piglet (0108-4#).

体细胞核移植

转基因猪克隆

In vitro development of re-cloned SCNT embryos generated using fibroblasts derived from a transgenic piglet (0108-4#).

NIAID Data Ecosystem40

Production of identical sextuplet mice by transferring metaphase nuclei from four-cell embryos

小鼠克隆技术

体细胞核移植

Mouse clones were produced by serial nuclear transfer commencing with the transfer of four-cell nuclei at metaphase into unfertilized ooplasts. The donor four-cell-stage nuclei were synchronized in me

PubMed Central1996-11-12 更新30

Histone Demethylase-Assisted Somatic Cell Nuclear Transfer Facilitates Derivation of Human Pluripotent Stem Cells

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