CancerTope: A Platform for Designing Genome-Based Personalized Immunotherapy or Vaccine against Cancer
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下载链接:
https://zenodo.org/doi/10.5281/zenodo.20065433
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Welcome to the official repository for Cancertope, a computational platform and database for identifying cancer-specific neoepitopes and designing personalized cancer vaccines and immunotherapies.
This resource integrates mutational data, immune epitope prediction, and vaccine candidate prioritization into a unified framework.
Citation
If you use Cancertope, please cite:
Gupta et al. (2016) A Platform for Designing Genome-Based Personalized Immunotherapy or Vaccine against Cancer PLOS ONE DOI: https://doi.org/10.1371/journal.pone.0166372
About the Platform
Cancertope is designed to address a key bottleneck in cancer immunotherapy:
Identifying tumor-specific antigens (neoantigens) that can trigger a targeted immune response.
Traditional experimental methods are:
Costly
Time-consuming
Not scalable
Cancertope solves this using computational pipelines + large-scale mutation data.
It analyzes:
Somatic mutations
Cancer-specific protein regions
Immune epitope potential
and converts them into actionable vaccine candidates .
提供机构:
Zenodo
创建时间:
2026-05-07



