Structure of rat neuronal nitric oxide synthase R349A mutant heme domain bound with N-(3-(((2-(3-(aminomethyl)-[1,1'-biphenyl]-4-yl)ethyl)amino)methyl)phenyl)thiophene-2-carboximidamide
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Structure of rat neuronal nitric oxide synthase R349A mutant heme domain bound with N-(3-(((2-(3-(aminomethyl)-[1,1'-biphenyl]-4-yl)ethyl)amino)methyl)phenyl)thiophene-2-carboximidamide Descriptor: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, N-{3-[({2-[3-(aminomethyl)[1,1'-biphenyl]-4-yl]ethyl}amino)methyl]phenyl}thiophene-2-carboximidamide, ... Authors: Li, H, Poulos, T.L. Deposit date: 2025-01-17 Release date: 2025-11-26 Last modified: 2026-04-01 Method: X-RAY DIFFRACTION (1.87 Å) Cite: New Inhibitors of Neuronal Nitric Oxide Synthase for the Treatment of Melanoma. J.Med.Chem., 69, 2026
创建时间:
2025-01-17



