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CD161 defines a transcriptional and functional phenotype shared across distinct human T cell lineages (CD 8)

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DataMed2026-07-12 收录
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T lymphocytes are conventionally divided into subsets based upon expression of co-receptors, cytokines and surface molecules. By mRNA microarray analysis, T lymphocytes that express the C-type lectin CD161 were identified to share a transcriptional profile, which led to the identification of an innate function across these previously defined subsets, including CD8, CD4 and TCRgd T cells.

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