Summary of cuticle phenotypes from various pathway mutants expressing the four forms of GSK-3.

For dsh, zw3, arr, and arm mutations embryos were maternally and zygotically (M/Z) mutant, whereas wg was only zygotically mutated. All crosses use second chromosome armGal4 except for arr mutants where third chromosome daGal4 was used. The wg phenotype refers to a wg-like embryo or a loss of signaling phenotype. Naked refers to a loss of denticles phenotype similar to ectopic Wg activation or loss of GSK-3. N.D. means that the experiment wasn't done. In zw3 mutant embryos, little paternal rescue is observed with half the embryos being completely naked and the other half mostly naked, so the rescue must involve a significant return to wild-type patterning only observed in UAS-GSK-3 expressing embryos. For dsh, arr, and arm mutations, paternal rescue is complete with 50% of embryos returning to a wild-type phenotype.Summary of cuticle phenotypes from various pathway mutants expressing the four forms of GSK-3.