rVSHV-SP_GE_WNV and rVSHV-SP_GE_WNVΔTMTM_G partially protect mice against a lethal WNV challenge.

(a) The percentage of weight loss was calculated everyday post-challenge during 15 days. This percentage is based on the variation of weight observed everyday compared to that measured the day of the WNV challenge. (b) Number of surviving mice on day 21 post-challenge. (c) WNV genomic RNA was detected by quantitative RT-PCR in the blood of mice collected on days 3 and 7 post-challenge.