Copper-Catalyzed Multicomponent Cascade Process for the Synthesis of Hexahydro-1<i>H</i>-isoindolones
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Copper-catalyzed coupling of imines, dienylstannanes, and acryloyl chlorides followed by a Diels−Alder reaction afforded hexahydro-1H-isoindolones. Diversification of the core via Pd-catalyzed cross-coupling defines a new modular approach to isoindolone combinatorial libraries.
创建时间：
2007-02-16
