Summary of effects for variables on hippocampal volume: APOE dose-dependent model.

n = 662.Results for model which treats APOE epsilon “X” allele effects as dose-dependent effects. APOE effect sizes of each variable are reported in terms of mm3/(unit variable), e.g., the effect of “Age” on the outcome variable, hippocampal volume, is −23.31 mm3/year of age. “:” denotes interaction terms between variables. Reference for the model is an APOE ε3/ε3 CN individual. Note the lack of a main effect of APOE epsilon 4 (“ApoE4”) in the model and thus in CN subjects.