Here, we performed an integrative analysis of scRNA-seq and scATAC-seq data from four ccRCC patients and aimed to identify the key regulatory molecules that mediate tumor development and manipulate th
IntroductionTumor Necrosis Factor Alpha is a known pro-inflammatory cytokine that plays a key role in the pathogenesis of rheumatoid arthritis. Anti-cytokine therapies targeting Tumor Necrosis Factor
The differential activity of transcription factors (TFs) manifests in a differential genome activation in different cell lineages and cell types. Here, we have mapped mRNA expression and accessible ch
