P38 in complex with Imatinib

P38 in complex with Imatinib Descriptor: 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside Authors: Namboodiri, H.V, Karpusas, M. Deposit date: 2009-05-08 Release date: 2009-11-10 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Analysis of imatinib and sorafenib binding to p38alpha compared with c-Abl and b-Raf provides structural insights for understanding the selectivity of inhibitors targeting the DFG-out form of protein kinases. Biochemistry, 49, 2010