Crystal structure of SARS-CoV-2 Mpro Mutant P132H with C5a
收藏Protein Data Bank Japan2025-11-26 更新2026-04-04 收录
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Crystal structure of SARS-CoV-2 Mpro Mutant P132H with C5a Descriptor: 3C-like proteinase nsp5, N-[(4-chlorothiophen-2-yl)methyl]-N-[4-(dimethylamino)phenyl]-2-(5-hydroxyisoquinolin-4-yl)acetamide Authors: Kenward, C, Mosimann, W.A, Worrall, L.J, Strynadka, N.C.J. Deposit date: 2025-07-04 Release date: 2025-07-16 Last modified: 2025-11-26 Method: X-RAY DIFFRACTION (2.69 Å) Cite: Functional and Structural Characterization of Treatment-Emergent Nirmatrelvir Resistance Mutations at Low Frequencies in the Main Protease (Mpro) Reveals a Unique Evolutionary Route for SARS-CoV-2 to Gain Resistance. J.Infect.Dis., 232, 2025
创建时间：
2025-07-04
