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Human soluble adenylyl cyclase in complex with the inhibitor TDI10229

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Protein Data Bank Japan2024-10-16 更新2026-03-28 收录
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Human soluble adenylyl cyclase in complex with the inhibitor TDI10229 Descriptor: 1,2-ETHANEDIOL, 4-chloranyl-6-[1,5-dimethyl-4-(phenylmethyl)pyrazol-3-yl]pyrimidin-2-amine, ACETATE ION, ... Authors: Steegborn, C, Quast, J. Deposit date: 2021-06-14 Release date: 2021-10-06 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Discovery of TDI-10229: A Potent and Orally Bioavailable Inhibitor of Soluble Adenylyl Cyclase (sAC, ADCY10). Acs Med.Chem.Lett., 12, 2021
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2021-06-14
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